If a CNS depressant or benzodiazepine are essential in a affected person already on an opioid analgesic: Initiate which has a decrease Original dose of the benzodiazepine or other CNS depressant; titrate depending on scientific reaction.Evaluate Just about every individual's threat prior to prescribing and observe all sufferers often for the event
If concomitant use is warranted, very carefully notice the individual, specifically for the duration of remedy initiation and dose adjustment. Discontinue oxycodone HCl if serotonin syndrome is suspected.Serotonin Syndrome Tell people that opioids could bring about a unusual but possibly lifetime-threatening affliction resulting from concomitant ad
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